PK Parameter         Emtricitabine         Rilpivirine         Tenofovir
Geometric
Least-Squares
Mean Ratio (%)
90% CI Geometric
Least-Squares Mean Ratio (%)
90% CI Geometric
Least-Squares Mean Ratio (%)
90% CI
Cmax 105 100 to 111 116 108 to 124 111 104 to 118
AUC0-last 99.9 97.8 to 102 116 109 to 123 102 99.0 to 105
AUCinf 99.9 97.7 to 102 116 109 to 123 102 99.1 to 105
CI = confidence interval; PK = pharmacokinetic
Data presented in 3 significant figures
Table 4: Statistical Comparisons of Emtricitabine, Rilpivirine, and Tenofovir Pharmacokinetic Parameters for Test Formulation 1 versus Reference Formulation.
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