PK Parameter
Emtricitabine
Rilpivirine
Tenofovir
Geometric
Least-Squares
Mean Ratio (%)
90% CI
Geometric
Least-Squares Mean Ratio (%)
90% CI
Geometric
Least-Squares Mean Ratio (%)
90% CI
C
max
105
100 to 111
116
108 to 124
111
104 to 118
AUC
0-last
99.9
97.8 to 102
116
109 to 123
102
99.0 to 105
AUC
inf
99.9
97.7 to 102
116
109 to 123
102
99.1 to 105
CI = confidence interval; PK = pharmacokinetic
Data presented in 3 significant figures
Table 4:
Statistical Comparisons of Emtricitabine, Rilpivirine, and Tenofovir Pharmacokinetic Parameters for Test Formulation 1 versus Reference Formulation.
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