Organ                                                                                 Ouabain concentration (M)                                   10-11                                 10-8                                10-6         H         SC        Δ%         H         SC         Δ%         H         SC        Δ% Heart muscle 18.11 ±0.4 18.67 ±0.1 ↑3.09 21.46 ±0.64 20.72 ±0.1 ↓3.46 25.14 ±0.49 25.87 ±0.1 ↑2.9 Skeletal muscle 16.65 ±0.38 17.28 ±0.39 ↑3.79 18.81 ±0.5 20.03 ±0.87 ↑6.52 23.75 ±0.5 24.67 ±0.26 ↑3.87 Lung 18.45 ±0.75 18.23 ±0.59 ↓1.21 21.44 ±1.06 21.92 ±0.29 ↑2.24 26.04 ±0.77 25.53 ±0.29 ↓1.99 Liver 17.39 ±0.38 15.79 ±0.48 ↓9.16 18.77 ±0.55 18.97 ±0.35 ↑1.08 24.25 ±0.45 23.52 ±0.08 ↓3.02 Spleen 18.49 ±0.63 17.32 ±1.14 ↓6.31 21.56 ±0.46 20.64 ±1.22 ↓4.3 24.99 ±0.48 25.19 ±1.81 ↑0.77 Kidney 17.06 ±0.61 16.95 ±0.43 ↓0.66 19.94 ±0.6 19.64 ±0.09 ↓1.5 24.51 ±0.52 24.61 ±0.66 ↑0.42 Sarcom-180   16.64 ±0.68     19.88 ±0.75     24.4 ±0.22

Table 3: 10-11M, 10-8M and 10-6M ouabain binding with α3, α2 and α1 receptors in tissues of different organs of healthy (H) and sarcoma-180 carrying (SC) mice.

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