Fa* |
Weight (mg)**
(n=20) |
Thickness (mm)**
(n=5) |
Hardness (kg/cm2)**
(n=6) |
Friability (%)**
(n=6) |
Drug content (%)**
(n=5) |
IR |
71.2 ± 1.3 |
3.23 ± 0.9 |
4.08 ± 0.5 |
0.19 ± 0.04 |
101.05 ± 1.4 |
F-1 |
69.71 ± 1.4 |
3.45 ± 0.05 |
4.02 ± 0.03 |
0.17 ± 0.03 |
98.91 ± 1.2 |
F-2 |
69.54 ± 1.56 |
3.35 ± 0.04 |
4.04 ± 0.07 |
0.13 ± 0.02 |
99.12 ± 1.3 |
F-3 |
70.56 ± 1.69 |
3.65 ± 0.06 |
4.07 ± 0.06 |
0.08 ± 0.02 |
101.1 ± 1.06 |
F-4 |
71.67 ± 1.45 |
3.65 ± 0.08 |
4.02 ± 0.02 |
0.07 ± 0.01 |
99.17 ± 1.4 |
F-5 |
68.67 ± 1.56 |
3.56 ± 0.03 |
4.03 ± 0.05 |
0.06 ± 0.03 |
101.23 ± 1.35 |
aCode of formulations, bResults represents the mean of replicate determination with the standard deviation given in parenthesis
*Fa – Code of formulations **All values represent mean ±SD (n=3) |