INGREDIENTS |
F1 |
F2 |
F3 |
F4 |
F5 |
F6 |
F7 |
F8 |
Phenytoin sodium |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
Avicel PH101 |
- |
- |
- |
55.15 |
54.3 |
54.2 |
- |
- |
Ethyl cellulose N-14 (14 cps) |
- |
- |
- |
4.25 |
8.5 |
7.5 |
- |
- |
HPMC |
- |
- |
- |
- |
- |
5.5 |
|
- |
HPMC-E15 |
- |
- |
- |
|
5.3 |
- |
- |
- |
HPMC- K4M |
- |
- |
- |
- |
- |
- |
40 |
|
Chitosan |
- |
- |
- |
- |
- |
- |
- |
40 |
Eudragit RSPO |
30 |
- |
- |
- |
- |
- |
- |
- |
Eudragit RS100 |
- |
|
30 |
8.5 |
- |
- |
- |
- |
Eudragit RL100 |
- |
30 |
- |
- |
- |
- |
- |
|
Lactose |
1.5 |
2 |
6.5 |
|
- |
- |
1.6 |
1.6 |
Mg.stearate |
1.5 |
1.8 |
2 |
1.7 |
1.7 |
1.5 |
1.5 |
1.5 |
Talc |
0.6 |
5.5 |
7 |
|
- |
- |
0.6 |
0.6 |
Colloidal
silicone dioxide |
- |
|
|
0.4 |
0.6 |
0.8 |
- |
- |
Starch |
5% |
5% |
5% |
- |
- |
- |
- |
- |
Purified water |
q.s |
q.s |
q.s |
q.s |
q.s |
q.s |
q.s |
q.s |
SLS |
7.5 |
7.5 |
6.5 |
3.25 |
6.5 |
7.5 |
3.25 |
6.5 |
F1, F2 and F3 formulations contain processed starch in percentage of 5%.
F5 and F6 formulations contain colloidal silicon dioxide in the percentage of 0.5-1%.
F5 and F6 formulations contain Avicel PH101 in the percentage of 53-55%. |