Parameters

Lipitor^® Tablets (Mean ± SEM)

Lipiget^® Tablets (Mean ± SEM)

C_max (ng/ml)

13.739 ± 0.210

13.374 ± 0.145ns

T_max(h)

1.222 ± 0.060

1.167 ± 0.057ns

AUC_0-∞ (ng h/ml)

73.955 ± 1.715

77.773 ± 1.858ns

AUMC_0-∞ (ng h²/ml)

623.518 ± 20.771

694.572 ± 31.073ns

MRT (h)

8.403 ± 0.127

8.903 ± 0.285ns

K_e(h^-1)

0.105 ± 0.003

0.105 ± 0.003ns

t_1/2(el) (h)

6.654 ± 0.164

6.756 ± 0.309ns

V_d (L/Kg)

5.249 ± 0.190

5.062 ± 0.252ns

Cl (ml/min)

0.519 ± 0.012

0.519 ± 0.012ns