Analyte
  Low concentration
Std solution Unextracted Extracted
11900 9470 3530
11700 9470 3540
11500 10000 3220
12000 8180 3570
11100 8750 3650
Mean 11640 9174 3502
CV (%) 3.1 7.8 4.7
Recovery 38.2
Matrix Effect -21.2
  Medium concentration
Std solution Unextracted Extracted
68800 44800 16400
66700 41700 16400
73300 43800 16300
66900 42000 16000
86600 44000 16100
Mean 72460 43260 16240
CV (%) 11.5 3.1 1.1
Recovery 37.5
Matrix Effect -40.3
  High concentration
Std solution Unextracted Extracted
289000 180000 60600
289000 178000 60400
268000 176000 58200
289000 177000 59300
337000 172000 57000
Mean 294400 176600 59100
CV (%) 8.7 1.7 2.6
Recovery 33.5
Mattrix Effect -40.0
Table 3: Matrix effect between spiked mobile phase solutions and unextracted samples, spiked on plasma residues for analyte and internal standard.
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