| |
Male
(Mean ± SD) |
Female
(Mean ± SD) |
t-test |
| AUC ([ng*hr]/mL) |
2382.96 ± 343.05 |
1705.59 ± 703.65 |
0.0136 |
| corrected by weight (ug/kg) |
34.07 ± 3.00 |
19.93 ± 8.18 |
0.0001 |
| corrected by BSA (ug/m2) |
0.88 ± 0.08 |
0.54 ± 0.21 |
0.0002 |
| CL (L/hr) |
1.76 ± 0.23 |
2.91 ± 1.41 |
0.0205 |
| corrected by weight (L/hr*kg) |
0.03 ± 0.003 |
0.06 ± 0.028 |
0.0036 |
| corrected by BSA (L/hr*m2) |
1.14 ± 0.09 |
2.14 ± 0.94 |
0.0036 |
|
