Parameter FF
Geometric Mean (95% CI)
VI
Geometric Mean (95% CI)
MAT (h) 10.53 (8.52, 13.01) 0.659 (0.286, 1.517)
T90 (h) 35.2 (32.0, 38.7) 3.83 (2.64, 5.57)
t½, abs (h) 8.76 (7.82, 9.81) 1.074 (0.775, 1.489)
CI = confidence interval; FF = fluticasone furoate; MAT = mean absorption time; t½,abs = absorption half-life; T90 = time for 90% to be absorbed; VI = vilanterol.
Table 4: Summary of FF and VI absorption pharmacokinetic parameters following inhaled administration of FF/VI 800/100 μg (absolute bioavailability Study 2).
Goto home»