Time [hours] Dose excretedin 0-264 hours [%]
Urine Faeces Total
0-4 h 1.15 ± 0.134 - -
4-8 h 1.14 ± 0.320 - -
8-12 h 0.65 ± 0.205 - -
12-24 h 0.98 ± 0.328 - -
0-24 h 3.92 ± 0.787 1.93 ± 1.691 5.07 ± 1.690
24-48 h 1.02 ± 0.317 2.91 ± 5.014 2.78 ± 3.927
48-72 h 0.50 ± 0.136 28.7 ± 22.82 23.47 ± 23.498
72-96 h 0.30 ± 0.094 16.0 ± 20.53 9.94 ± 16.907
96-120 h 0.23 ± 0.083 11.2 ± 10.01 9.13 ± 10.053
120-144 h 0.15 ± 0.071 7.76 ± 4.745 7.93 ± 4.790
144-168 h 0.13 ± 0.054 2.38 ± 1.318 2.00 ± 1.636
168-192 h 0.10 ± 0.030 4.33 ± 6.919 3.50 ± 6.279
192-216 h 0.09 ± 0.026 9.77 ± 17.90 9.84 ± 17.920
216-240 h NC 4.69 ± 9.510 4.68 ± 9.510
240-264 h NC 0.60 ± 0.539 0.60 ± 0.539
Subtotal 6.35 ± 1.616 72.50 ± 4.574 78.80 ± 3.606
Table 2: Mass balance of radioactivity after a single oral dose of [14C]ulipristal acetate in healthy premenopausal women (n=5). Data are presented as mean ± standard deviation
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