Chemical drugs Biologic drugs
Made by chemical synthesis Made by living cells
Defined structure Heterogeneous structure
Mixtures of related molecules
Easy to characterize Difficult to characterize
Relatively stable     No issue of immunogenicity Variable
Sensitive to environmental conditions
such as light and temperature Issue of immunogenicity
Usually taken orally Usually injected
Often prescribed by a general practitioner Usually prescribed by specialists
Table 1: Fundamental Differences.
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