Capecitabine / Xeloda 150 mg (n = 8)
Capecitabine in fasting conditions
Parametric Analysis
Geom. Mean
90% CI
Power
Intra-subject CV
C
max
95.71
64.35 - 142.35
0.2251
42.61%
AUC
last
107.99
98.36 - 118.57
0.9825
9.64%
AUC
inf
107.93
98.34 - 118.45
0.9829
9.60%
Capecitabine / Xeloda 150 mg (n = 8)
Capecitabine in fed conditions
Parametric Analysis
Geom. Mean
90% CI
Power
Intra-subject CV
C
max
147.67
76.47 - 285.17
0.1434
76.27%
AUC
last
113.92
93.7 - 138.51
0.6069
20.31%
AUC
inf
113.95
93.83 - 138.39
0.6115
20.19%
Table 5:
Geometric mean of the individual AUC
last
, AUC
inf
and C
max
ratios (test/ reference), the respective 90% confidence intervals (CI), power and CV.
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