Formulation code Coating thickness (cm) Average weight
(mg)
Hardness
(kg / cm2)
Friability (%) Disintegration
Time (h)
Bursting time (hr)n
  Diameter Thickness          
FM1 0.218±0.001 0.198±0.003 866.03±8.78 6.24±0.32 0.89±0.11 3.24±0.012 5.05±0.18
FM2 0.228±0.002 0.198±0.002 866.33±6.28 6.31±0.37 0.86±0.10 3.50±0.013 5.18±0.08
FM3 0.237±0.001 0.210±0.003 866.14±6.69 6.24±0.29 0.87±0.15 3.55±0.012 5.25±0.15
FM4 0.219±0.001 0.205±0.002 865.23±9.20 6.26±0.31 0.84±0.16 4.05±0.011 4.24±0.13
FM5 0.229±0.001 0.199±0.003 864±7.211 6.31±0.36 0.83±0.10 4.44±0.012 4.45±0.10
n = 3              
Table 4: Physical characterization of metronidazole delivery system (FM1 to FM5).
Goto home»