Table 3 |
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Intra and Inter accuracy and precision for topiramate |
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Topiramate intra assay precision and accuracy |
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Topiramate inter assay precision and accuracy |
Quality control samples |
Conc. added (ng/ml) |
Mean conc. found (ng/ml) (a) |
SD |
Precision % CV |
Accuracy (%) |
Mean conc. found (ng/ml) (b) |
SD |
Precision % CV |
Accuracy (%) |
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LLOQ |
10 |
9.870 |
1.018 |
10.32 |
98.70 |
9.923 |
1.271 |
12.81 |
99.23 |
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LQC |
30 |
30.907 |
0.691 |
2.24 |
103.02 |
30.705 |
1.470 |
4.79 |
102.35 |
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MQC |
1500 |
1503.451 |
83.393 |
5.55 |
100.23 |
1489.480 |
104.147 |
6.99 |
99.30 |
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HQC |
3000 |
2994.612 |
83.271 |
2.78 |
99.82 |
3093.498 |
49.904 |
1.61 |
103.12 |
(a) = mean of six replicates |
|
(b) = mean of thirty replicates |
Conc. = Concentration |
