| Time
(hours) |
Animal Groups |
| Control (Group I) |
DOCA salt
(Group II) |
DOCA salt + Formulation
(Group III) |
DOCA salt + Pure Drug
(Group IV) |
| Systolic BP |
Diastolic BP |
Systolic BP |
Diastolic BP |
Systolic BP |
Diastolic BP |
Systolic BP |
Diastolic BP |
| 0 hr |
120 ± 0.40 |
91 ± 0.7 |
162 ± 1.35* |
119 ± 1.08* |
164 ± 1.08# |
118 ± 0.82# |
163 ± 0.71## |
119 ± 0.42## |
| 1 hr |
119 ± 0.82 |
92 ± 1.23 |
164 ± 0.81* |
120 ± 0.58* |
153 ± 1.58# |
115 ± 0.91# |
142 ± 1.08## |
108 ± 1.07## |
| 2 hr |
121 ± 0.7 |
90 ± 1.08 |
162 ± 1.23* |
121 ± 0.71* |
148 ± 0.41# |
109 ± 0.912# |
131 ± 1.59## |
102 ± 0.41## |
| 6 hr |
120 ±0.91 |
91 ± 0.40 |
163 ± 2.34* |
120 ± 1.47* |
139 ± 1.23# |
103 ± 0.57# |
132 ± 1.68## |
101 ± 0.71## |
| 12 hr |
122 ± 1.08 |
91 ± 1.22 |
162 ± 0.41* |
119 ± 1.68* |
129 ± 0.91# |
97 ± 1.23# |
137 ± 1.0## |
100 ± 1.04## |
| 24 hr |
120 ± 1.0 |
92 ± 0.82 |
163 ±
1* |
119 ± 1.15* |
126 ± 0.41# |
94 ± 1.08# |
139 ± 0.87## |
101 ± 0.85## |
BP- Blood pressure, DOCA- Deoxycorticosterone acetate.
Data expressed in Mean ± SEM. n = 4. Statistical analysis is done by One-way Analysis of Variance followed by Tukey’s Multiple Comparison Test. *P<0.001: when
compared with Control Group; #P<0.05: When compared with DOCA Treated group; ##P<0.001: when compared with DOCA Treated group. |
