Method

logP_oct Melatonin

ALOGPS2.1

1.42

AC_logP

1.68

AB/LogP

1.34

miLogP

1.45

ALOGP

1.56

MLOGP

1.36

KOWWIN

1.65

XLOGP2

1.56

Pallas 3.7^a

1.41

Moriguchi's method^b

1.58

Average

1.5