| Group |
Parameter |
Human subjects |
Experimental animals |
| Control |
Lead exposed |
Control |
Low dose exposure (2000 ppm) |
High dose exposure
(4000 ppm) |
| T3 (ng/dl) |
118.53 ± 23.54 |
116.64 ± 22.02 |
4.61 ± 1.06 |
5.96 ± 0.94 |
8.47a,b ± 1.22 |
| T4 (µg/dl) |
8.29 ± 1.59 |
7.42 ± 1.71 |
49.38 ± 5.5 |
62.57 ± 9.01 |
94.47a,b ± 15.87 |
| Testosterone (ng/ml) |
3.98 ± 1.38 |
1.64a ± 0.65 |
11.5 ± 0.73 |
9.05a ± 1.46 |
6.87a,b ± 0.48 |
| Cortisol (µg/dl) |
6.07 ± 2.51 |
10.69a ± 1.96 |
2.16 ± 0.49 |
1.2a± 0.26 |
0.70a,b ± 0.52 |
Results are presented as means ± SD (n=8 for each mice group and 15 for human group)
a=Significant difference (P <0.05) comparing to the normal control group (mice or human)
b=Significant difference (P<0.05) comparing to 2000 ppm lead acetate (low dose) group |
