| Variable |
Antiretroviral regimens prescribed from 2000 to 2009 |
Total number of patients (%) |
| AZT/3TC
/NVP |
d4T/3TC
/NVP |
AZT/3TC
+EFV |
TDF/FTC
+NVP |
AZT+
TDF/FTC
+LPV/r |
TDF/FTC
/EFV |
d4T/3TC+EFV |
| Patients per regimen (%) |
2025 (55.6) |
1145 (31.4) |
78 (2.1) |
170 (4.7) |
160 (4.4) |
58 (1.6) |
5 (0.1) |
3641 (100.0) |
| Incidence of ADR per 100 –person years |
8.1 |
8.7 |
60.3 |
21.2 |
19.4 |
3.4 |
0 |
|
| Patients with ADR (%) |
164 (4.5) |
100 (2.7) |
47 (1.3) |
36 (1.0) |
31 (0.9) |
2 (0.05) |
0 (0.0) |
380 (10.4) |
| Type of ADRs |
|
|
|
|
|
|
|
|
| Nausea, vomiting,
hyper
salivation |
40 (10.5) |
22 (5.8) |
23 (6.1) |
24 (6.3) |
20 (5.3) |
0 |
0 |
129 (34.0) |
| Skin rash |
62 (16.3) |
38 (10.0) |
0 |
0 |
0 |
0 |
0 |
100(26.3) |
| Anemia |
24 (6.3) |
|
|
|
3 (0.8) |
|
|
27(7.1) |
| Steven-Johnson Syndrome |
7 (1.8) |
20 (5.3) |
0 |
0 |
0 |
0 |
0 |
27(7.1) |
| Diarrhea |
0 |
0 |
0 |
10 (2.6) |
8 (2.1) |
0 |
0 |
18(4.7) |
| Jaundice |
16 (4.2) |
0 |
0 |
0 |
0 |
0 |
0 |
16(4.2) |
| Peripheral neuritis |
0 |
12 (3.2) |
0 |
0 |
0 |
0 |
0 |
12 (3.2) |
| Discoloration of fingernails |
10 (2.6) |
0 |
0 |
0 |
0 |
0 |
0 |
10 (2.6) |
| Insomnia |
0 |
0 |
10 (2.6) |
0 |
0 |
0 |
0 |
10 (2.6) |
| Proximal muscle pain and weakness |
5 (1.3) |
0 |
2 (0.5) |
2 (0.5) |
0 |
0 |
0 |
9 (2.3) |
| Somnolence |
0 |
0 |
7 (1.8) |
0 |
0 |
0 |
0 |
7 (1.8) |
| Facial lipo-
dystrophy |
0 |
6 (1.6) |
0 |
0 |
0 |
0 |
0 |
6 (1.6) |
| Bad dreams |
0 |
0 |
4 (1.1) |
0 |
0 |
2 (0.5) |
0 |
6 (1.6) |
| Palmhyper
pigmentation |
0 |
2 (0.5) |
0 |
0 |
0 |
0 |
0 |
2(0.5) |
| Severe headache |
0 |
0 |
1 (0.3) |
0 |
0 |
0 |
0 |
1(0.3) |
