Causes Value (%) Overall 83 (35.8) Switch 19 (8.2) Pregnancy 6 (2.6) Drug-drug interaction 1 (0.4) Therapeutic failure Any 57 (24.6) Intolerance/Side effects 30 (12.9) Neurological Hepatotoxicity Nefrotoxicity Gastrointestinal intolerance Skin rash Metabolic disorder Anemia 11 (4.7) 1 (<1) 2 (<1) 2 (<1) 9 (3.9) 1 (<1) 4 (1.7)      Virological failure 13 (5.6)      Lost to follow up 11 (4.7)      Death 3  (1.3)

Table 3: Causes of discontinuation of the initial antiretroviral regimen.

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