Selected laboratory tests Toxicity criteriaa
Hepatic markers
Alkaline phosphatase >5×ULN
Aspartate aminotransferase >5×ULN
Alanine aminotransferase >5×ULN
Serum lipids
Fasting total cholesterol >300 mg/dl
Fasting LDL-C ≥190 mg/dl
Fasting triglycerides >750 mg/dl
Other markers
Amylase >2×ULN
Creatine kinase >10×ULN
Note: DAIDS - Division of AIDS; LDL-C- low-density lipoprotein cholesterol; ULNupper limit of normal.
aGrades 3/4 by DAIDS criteria [12]
Table 1: Toxicity criteria as defined by DAIDS [12].
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