Selected laboratory tests |
Toxicity criteriaa |
Hepatic markers |
Alkaline phosphatase |
>5×ULN |
Aspartate aminotransferase |
>5×ULN |
Alanine aminotransferase |
>5×ULN |
Serum lipids |
Fasting total cholesterol |
>300 mg/dl |
Fasting LDL-C |
≥190 mg/dl |
Fasting triglycerides |
>750 mg/dl |
Other markers |
Amylase |
>2×ULN |
Creatine kinase |
>10×ULN |
Note: DAIDS - Division of AIDS; LDL-C- low-density lipoprotein cholesterol; ULNupper
limit of normal.
aGrades 3/4 by DAIDS criteria [12] |