|
| Figure 5: Antiviral activity of GRFT in the DC-SIGN mediated HIV transmission pathway. The following light microscopical pictures show respectively: R5/X4 HIV-1 strain HE captured by Raji.DC-SIGN cells (Raji. DC-SIGN/HE; panel a), CD4+ target C8166 T cells (panel b), hugegiant cell formation after 24 h of coculture (panel c), dose-dependent protective effect of GRFT against HIV-1 transmission at 0.31 nM (panel d), 0.063 nM (panel e) and 0.013 nM (panel f). Magnification×10/0.25. |
