Genomic organization and ORFs arrangement are based on the viral sequence of the VZV pOka strain (parental strain of WT VZV). Each VZV ORF is color-coded according to the growth properties of its corresponding virus gene-deletion mutant in cultured MeWo cells and human fetal skin organ cultures. The blue lines for ORF42 represent a splicing junction. For all growth curves, wild-type infections served as positive controls and mock infections served as negative controls.
*Image adapted from Selariu et al.
