| Electrical
methods |
Biological information |
Reference |
| Impedancemetry |
-cell size, membrane conductivity & intracellular structures
-cell growth & invasion, adherence, cell spreading
-cell swelling & lysis, cell death
-cell migration
-epithelial membrane integrity & polarity
-cell status (normal, apoptotic, necrotic)
-cell differentiation
-cell mitosis & motility
-cell shape / cell culture density; spheroids properties |
-Debuisson, 2008; Cheung 2010 (rev)
-Rahim et al, 2011
-Malleo et al, 2010; Cheung 2010 (rev)
-Wang et al, 2008
-Sun et al, 2010
-Gou et al, 2010
-Hildebrandt et al, 2010; Cheung 2010
-Ghenim et al, 2010
-KloB et al, 2008 |
| Amperometry |
cell secretion (metabolites, enzyme activity); exocytosis |
Amatore, 2010 (book chapter); Spegel et al (2008); Bao et al (2008) (rev). |
| Patch-clamp |
ion channels activity from single cells |
Picollet (book chapter) 2010, Dunlop et al (2008) (rev) |
| Capacitive biosensors |
membrane protein activity; metabolic activity |
Levine et al, 2009; Tsouti et al 2011 (rev) |
| FET |
extracellular currents |
Fromherz (2001); Yu et al, 2007 |
| nanoFET |
extra- + intracellular activity in a sub-10 nm-scale : local action potential signals, mapping functional connectivity.
Prospects: correlate electronic signalling with chemical release |
Tian et al, 2010
Timko et al, 2010 |
| MEAs |
MEAs |
MEAs |
| MEAS + patch-clamp |
communicating networks + intracellular recordings; cell-to-cell communication |
Py et al, 2010 |
