| Characteristic |
Completers (n = 38) |
Non-completers (n = 27) |
p |
| Plasma GGT, U/L; mean (SD)
(reference range 8-61) |
212.95 (452.14) |
114.30 (137.74) |
t = 1.10, 63 df, p = 0.28 |
| Plasma ALT, U/L; mean (SD)
(reference range < 41) |
34.76 (26.66) |
37.07 (30.21) |
t = - 0.33, 63 df, p = 0.75 |
| Plasma AST, U/L; mean (SD)
(reference range < 37) |
41.74 (40.54) |
39.67 (31.99) |
t = 0.22, 63 df, p = 0.83 |
| Plasma MCV, f/L; mean (SD)
(reference range 80-100) |
95.94 (5.20) |
94.30 (9.83) |
t = 0.85, 63 df, p = 0.40 |
| CIWA-AR, mean (SD) |
13.58 (9.70) |
13.81 (8.54) |
t = -0.10, 63 df, p = 0.92 |
| SADD, mean (SD) |
25.97 (7.15) |
27.33 (9.07) |
t = - 0.67, 63 df, p = 0.50 |
| OCDS, mean (SD) |
46.39 (8.67) |
46.41 (11.09) |
t = < -0.01, 63 df, p > 0.99 |
| HDRS, mean (SD) |
9.50 (5.79) |
9.70 (4.70) |
t = - 0.15, 63 df, p = 0.88 |
Biological markers were measured and instruments were applied over two weeks
before the beginning of double-blind study. GGT, Gamma-Glutamyl Transferase;
ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; MCV: Mean
Cellular Volume; CIWA-AR: Clinical Institute Withdrawal Assessment; SADD, Short
Alcohol Dependence Data; OCDS: Obsessive-Compulsive Drinking Scale; HDRS:
Hamilton Depression Rating Scale. |
