Temazepam 0 mg (Placebo)
Temazapam 30 mg
p^
Test
Index
Baseline
Post—tx
SRT2-SRT1 -Psychomotor Fatigue
Reaction Time (ms)
-1.86±43.13
8.14±25.48
24.89±37.52
10.78±29.71
0.85
CRT -Attention/ Working Memory
Reaction time (ms)
886.43±55.66
888.11± 38.36
890.61±86.54
865.00±64.45
0.42
Correct (%)
89.46±8.46
94.59±5.79
85.63±19.92
94.96±4.24
0.89
1–Back -Working Memory
795.21±77.31
837.64±61.46
871.11±156.21
853.17±82.23
0.68
93.56±8.15
94.9±5.67
92.60 ±6.97
95.60±5.13
0.80
2–Back -Working Memory
920.36±69.33
960.43±189.42
1052.83±202.44
923.72±176.79
0.70
74.86±10.27
77.1±8.26
72.73±15.92
72.33±18.61
0.54
HVLT-R -Verbal Learning/ Episodic Memory
Total words recalled (#)
21.14±7.52
21.86±5.24
21.33±4.92
21.11±3.86
0.75
Delayed Recall (%)
78.91±13.69
61.29±26.79
77.50±20.57
66.89±27.50
0.69
BVMT-R -Visuospacial Learning/ Episodic Memory
Total objects recalled (%)
13.57±4.20
11.57±4.16
15.67±5.50
13.44±3.54
0.35
87.14±20.58
94.0±21.26
91.78±37.67
94.11±20.65
0.99
Stroop Test -Selective Attention
Words Read (#)
84.86±18.88
88.57±14.68
86.89±15.19
88.11±13.59
0.95
Colors Read (#)
62.00±9.24
62.29±9.76
59.89±9.52
66.89±8.15
0.32
Color-Words Read (#)
36.43±11.66
38.57±10.28
35.89±7.39
39.89±7.64
0.77
Interference
1.00±10.13
2.00±8.33
0.56±7.20
1.67±5.20
0.92
COWAT -Verbal Fluency
Words Pronounced (#)
12.57±4.20
14.86±5.27
10.33±2.50
12.78±5.14
0.44
SST -Response Inhibition
RT – Go Trials (ms)
584.74±97.80
586.02±124.38
650.96±128.42
573.73±183.88
0.40
Baseline Accuracy (%)
98.90±1.20
98.53±1.50
93.95±8.47
95.40±5.13
0.24
SSRT (ms)
175.60±60.77
145.16±36.76
190.41±46.77
216.02±66.86
0.08
Table 2 : Baseline and post-treatment (post—tx) performance on neurocognitive functioning