| Study |
Population |
Dosage |
Side Effects (including percentage experiencing a given side effect) |
| Boudrez et al. [56] |
Non-psychiatric |
Not specified |
Nausea (8.9%), insomnia (2.9%), and sleep disorder (2.2%) |
| Gonzales et al. [57] |
Non-psychiatric |
1 mg BID |
Nausea (28%), insomnia (14%), dry mouth (6.7%), headache (15.5%), and dizziness (6%) |
| Jorenby et al. [59] |
Non-psychiatric |
1 mg BID |
Nausea (29.4%), insomnia (14.2%), abnormal dreams (13.1%), headache (12.8%), and dry mouth (5.5%) |
| Nides et al. [61] |
Non-psychiatric |
1 mg BID |
Nausea (52%), insomnia (35.2%), headache (24%), abnormal dreams (15.2%), and taste perversion (15.2%) |
| Garza et al. [85] |
Non-psychiatric |
1 mg BID |
Nausea (37.7%), insomnia (30.9%), somnolence (20%), and abnormal dreams (9.1%) |
| Evins and Goff, [88] |
Schizophrenia |
1 mg BID |
Nausea and vomiting (21.1%) |
| Stapleton et al. [89] |
Mentally Ill |
Not specified |
Nausea (32.1%), and sleep disturbances (32.1%) |
| Smith et al. [90] |
Schizophrenia, schizoaffective |
1 mg BID |
Mild nausea, shaking, dry mouth, and tiredness-sleepiness (57% of all patients experienced at least one side effect) |
| Weiner et al. [91] |
Schizophrenia |
1 mg BID |
Constipation (50%), insomnia (75%), and nausea (75%) |
| Liu et al. [92] |
Schizophrenia |
1 mg BID |
Nausea (10%), vomiting (10%), fatigue (5%), dry mouth (5%), muscle stiffness (5%), and headache (5%) |
| McClure et al. [97] |
Depression |
1 mg BID |
Tension (51%), nausea (61.6%), sleep disturbance (46.4%), irritability (47.1%), confusion (19.3%), and difficulty concentrating (33.4%) |
| Philip et al. [98] |
Depression |
1 mg BID |
GI problem (21.4%), sleep disturbances, and irritability (7.1%) |
| Tonstad et al. [99] |
Non-psychiatric |
1 mg BID |
Sleep disturbance (19.9%) |
|
