| |
Lipohypertrophy |
Lipoatrophy |
Lipodystrophy |
| Model 1* |
Model 1f |
Model 1‡ |
| Gender |
|
|
|
| Male |
1.00 |
1.00 |
1.00 |
| Female |
1.58 (1.37–1.82) |
0.92 (0.82–1.03) |
1.02 (0.95–1.10) |
| P value |
<0.001 |
0.16 |
0.5 |
| Age (years) |
1.01 (1.00 – 1.01) |
1.00 (1.00–1.01) |
1.004 (1.00–1.01) |
| P value |
0.06 |
0.9 |
0.04 |
| Skin color |
|
|
|
| Caucasian |
1.00 |
1.00 |
1.00 |
| Non - Caucasian |
1.07 (0.94–1.23) |
1.26 (1.12–1.41) |
1.13 (1.05–1.21) |
| P value |
0.3 |
< 0.001 |
< 0.001 |
| Education (years) |
1.01 (0.99 – 1.02) |
0.97 (0.96 – 0.99) |
0.99 (0.98 – 0.99) |
| P value |
0.4 |
<0.001 |
0.03 |
| |
Model 2** |
Model 2f |
Model 2‡ |
| Smoking (pack–years) |
|
|
|
| 0 |
1.00 |
1.00 |
1.00 |
| 1-19 |
0.81 (0.68–0.97) |
1.06 (0.92–1.21) |
1.00 (0.92–1.08) |
| ≥20 |
0.81 (0.70–0.95) |
1.07 (0.93–1.25) |
0.99 (0.91–1.09) |
| P value |
0.01 |
0.6 |
1.0 |
| Physical activity (min/week) |
|
|
|
| ≥150 |
1.00 |
1.00 |
1.00 |
| <150 |
1.05 (0.91–1.20) |
0.96 (0.86–1.08) |
1.01 (0.94–1.08) |
| P value |
0.5 |
0.5 |
0.9 |
| |
Model 3*** |
Model 3ff |
Model 3‡‡ |
| Body mass index (kg/m2) |
1.07 (1.06–1.09) |
0.96 (0.95–0.98) |
1.007 (1.00–1.01) |
| P–value |
<0.001 |
<0.001 |
0.04 |
| CD4 (cells/mm3) |
|
|
|
| ≥350 |
1.00 |
1.00 |
1.00 |
| 200-349 |
1.11 (0.96–1.28) |
0.99 (0.87–1.13) |
1.02 (0.95–1.11) |
| <200 |
0.83 (0.67–1.05) |
0.98 (0.85–1.13) |
0.95 (0.86–1.05) |
| P value |
0.049 |
1.0 |
0.4 |
| Viral load (copies/mL) |
|
|
|
| <50 |
1.00 |
1.00 |
1.00 |
| ≥50 |
0.78 (0.67–0.91) |
1.04 (0.93–1.16) |
0.96 (0.89–1.04) |
| P value |
0.001 |
0.5 |
0.3 |
| Time since diagnosis of HIV infection (years) |
|
|
|
| <3 |
1.00 |
1.00 |
1.00 |
| 3-5 |
1.02 (0.87–1.22) |
0.97 (0.82–1.14) |
1.01 (0.91–1.12) |
| ≥6 |
1.11 (0.95–1.29) |
1.18 (1.02–1.37) |
1.12 (1.02–1.22) |
| P value |
0.4 |
0.005 |
0.01 |
* Adjusted for gender and age
** Adjusted for gender, age, and smoking status
*** Adjusted for gender, age, smoking status, BMI, CD4, and viral load
fAdjusted for gender, skin color and education
ffAdjusted for gender, skin color, education, time since HIV diagnosis, and BMI
‡Adjusted for age, skin color, and education
‡‡Adjusted for age, skin color, education, time since HIV diagnosis, and BMI |
|
