| Variable |
Control (n=202) |
Cases (n=78) |
Univariate Odds Ratio (95%CI) |
P value |
Age(years ± SD)
[Range] |
Mean |
35.35 ± 7.58 |
38.10 ± 7.89 |
0.95 (0.92,0.98) |
0.008 |
| |
[20-62] |
[24-63] |
|
| Sex |
Male |
146 (72.3%) |
66 (84.6%) |
2.11(1.06,4.19) |
0.031 |
| Female |
56 (27.7%) |
12 (15.4%) |
|
| Baseline CD4 count ± SD |
Mean |
206.93 ± 169.91 |
103.92 ± 87.27 |
1.06(1.01,1.09) |
<0.0001 |
| Patients who had TB(%) |
0 times |
135 (66.83%) |
32 (41.1%) |
0.36(0.23,0.56) |
<0.0001 |
| 1 times |
62 (30.69%) |
34(43.6%) |
|
| 2 times |
05 (2.45%) |
12 (15.4%) |
|
| Taken private treatment(%) |
Yes |
93 (46%) |
37 (47.4%) |
|
0.798 |
| No |
109 (54%) |
41 (52.6%) |
|
| Last NRTI regimen |
Stavudine |
131(64.9%) |
47 (60.2%) |
|
0.315 |
| Zidovudine |
71 (35.1%) |
31 (39.7%) |
|
| Negative change in weight in last 24 months* |
Yes |
66 (32.7%) |
57 (73.1%) |
1.36(3.5,11.63) |
<0.0001 |
| No |
136 (67.3%) |
18 (23.1%) |
|
| Peak CD4 count during first line treatment ± SD(Range) |
Mean |
676.70 ± 276.20 |
236.19 ± 165.88 |
1.001(1.00,1.01) |
<0.0001 |
| |
(57-1809) |
(12-977) |
|
| Time duration for peak CD4 count ± SD(Range) |
Mean |
45.02 ± 12.60 |
21.89 ± 21.55 |
1.14(1.10,1.17) |
<0.0001 |
| |
(12-72) |
(05-156) |
|
* 3 patients on second line had no weight change available. SD= Standard deviation |
