| 
      Note: OR: Odds Ratio; CI: Confidence Interval
        |  | Unprotected Sex-MSP | Impaired Last Sex |  
        |  | Latent Class Only | Class & Covariates | Latent Class Only | Latent Class Only |  
        |  | OR (95% CI) | Sig | AOR (95% CI) | Sig | OR (95% CI) | Sig | AOR (95% CI) | Sig |  
        | Latent Classes |  | <0.0001 |  | 0.07 |  | <0.0001 |  | 0.02 |  
        | Marijuana and Alcohol    vs. Polydrug Use (ref) | 0.38 (0.25-0.57) | <0.0001 | 0.58 (0.36-0.94) | 0.03 | 0.41 (0.29-0.58) | <0.0001 | 0.76 (0.49-1.17) | 0.22 |  
        | High AOD Risk vs.    Polydrug Use (ref) | 0.95 (0.59-1.55) | 0.84 | 0.69 (0.41-1.15) | 0.15 | 1.70 (1.15-2.51) | 0.008 | 1.52 (1.01-2.29) | 0.05 |  
        | High AOD Risk vs.    Marijuana and Alcohol (ref) | 2.51 (1.59-3.95) | <0.0001 | 1.19 (0.68-2.07) | 0.55 | 4.17 (2.78-6.25) | <0.0001 | 1.99 (1.21-3.28) | 0.006 |  
        | Age |  |  |  | 0.14 |  |  |  | 0.08 |  
        | 18-24 vs. 25+ |  |  | 0.73 (0.48-1.11) |  |  |  | 0.73 (0.52-1.04) |  |  
        | Ethnicity |  |  |  | 0.005 |  |  |  | <0.0001 |  
        | Black African vs.    Coloured (ref) |  |  | 0.49 (0.30-0.81) |  |  |  | 0.33 (0.21-0.50) |  |  
        | Education |  |  |  | 0.61 |  |  |  | 0.64 |  
        | Less than 11th vs    12th+ |  |  | 1.16 (0.66-2.06) |  |  |  | 1.14 (0.67-1.94) |  |  
        | HIV Status |  |  |  | 0.001 |  |  |  | 0.1 |  
        | HIV- vs. HIV+ (ref) |  |  | 2.09 (1.34-3.27) |  |  |  | 0.69 (0.45-1.07) |  |  
        | Unemployment |  |  |  | 0.28 |  |  |  | 0.54 |  
        | Employed vs Unemployed |  |  | 0.72 (0.39-1.32) |  |  |  | 0.84 (0.48-1.47) |  |  | 
  
    | Table 4 (A): Logistic regression analyses of alcohol and other drug use (AOD) latent classes on sex behavior outcomes. | 
  
    | 
      
        |  | Unprotected Last Sex |  
        |  | Latent Class Only | Class & Covariates |  
        |   | OR (95% CI) | Sig | AOR (95% CI) |  
        | Latent Classes  |  | <0.0001 |  | 0.25 |  
        | Marijuana and Alcohol    vs. Polydrug Use (ref)  | 0.41 (0.29-0.60) | <0.0001 | 0.68 (0.44-1.07) | 0.1 |  
        | High AOD Risk vs.    Polydrug Use (ref) | 1.16 (0.75-1.80) | 0.52 | 0.90 (0.56-1.43) | 0.65 |  
        | High AOD Risk vs.    Marijuana and Alcohol (ref) | 2.79 (1.82-4.28) | <0.0001 | 1.31 (0.78-2.22) | 0.31 |  
        | Age |  |  |  | 0.05 |  
        | 18-24 vs. 25+ |  |  | 0.68 (0.46-0.99) |  |  
        | Ethnicity |  |  |  | 0.001 |  
        | Black African vs.    Coloured (ref) |  |  | 0.46 (0.29-0.72) |  |  
        | Education |  |  |  | 0.56 |  
        | Less than 11th vs    12th+ |  |  | 1.18 (0.68-2.02) |  |  
        | HIV Status  |  |  |  | 0.01 |  
        | HIV- vs. HIV+ (ref) |  |  | 1.74 (1.13-2.66) |  |  
        | Unemployment |  |  |  | 0.91 |  
        | Employed vs Unemployed |   |   | 0.97 (0.55-1.72) |   |  | 
  
    | Table 4 (B): Logistic regression analyses of alcohol and other drug use (AOD) latent classes on sex behavior outcomes. | 
  
    | 
      Note: OR: Odds Ratio; AOR: Adjusted Odds Ratio; CI: Confidence Interval
        |  | AOD to Unprotected Sex - MSP | AOD to Unprotected Sex –     Participant |  
        |  | Latent Class Only | Class & Covariates | Latent Class Only | Class & Covariates |  
        |   | OR (95% CI) | Sig | AOR (95% CI) | Sig | OR (95% CI) | Sig | AOR (95% CI) | Sig |  
        | Latent Classes  |  | <0.0001 |  | 0.34 |  | <0.0001 |  | 0.24 |  
        | Marijuana and Alcohol    vs. Polydrug Use (ref)  | 0.47 (0.29-0.75) | 0.002 | 0.91 (0.51-1.63) | 0.76 | 0.61 (0.39-0.93) | 0.02 | 1.01 (0.59-1.75) | 0.96 |  
        | High AOD Risk vs.    Polydrug Use (ref) | 1.56 (1.02-2.39) | 0.04 | 1.34 (0.85-2.11) | 0.2 | 1.63 (1.09-2.45) | 0.02 | 1.42 (0.93-2.18) | 0.11 |  
        | High AOD Risk vs.    Marijuana and Alcohol (ref) | 3.35 (2.05-5.48) | <0.0001 | 1.47 (0.80-2.72) | 0.22 | 2.70 (1.71-4.24) | <0.0001 | 1.40 (0.79-2.50) | 0.25 |  
        | Age |  |  |  | 0.08 |  |  |  | 0.13 |  
        | 18-24 vs. 25+ |  |  | 0.70 (0.47-1.05) |  |  |  | 0.75 (0.51-1.09) |  |  
        | Ethnicity |  |  |  | <0.0001 |  |  |  | 0.0003 |  
        | Black African vs.    Coloured (ref) |  |  | 0.31 (0.18-0.55) |  |  |  | 0.37 (0.22-0.64) |  |  
        | Education |  |  |  | 0.02 |  |  |  | 0.02 |  
        | Less than 11th vs    12th+ |  |  | 2.78 (1.14-6.81) |  |  |  | 2.77 (1.21-6.35) |  |  
        | HIV Status  |  |  |  | 0.94 |  |  |  | 0.87 |  
        | HIV- vs. HIV+ (ref) |  |  | 0.98 (0.54-1.76) |  |  |  | 1.05 (0.61-1.81) |  |  
        | Unemployment |  |  |  | 0.13 |  |  |  | 0.16 |  
        | Employed vs Unemployed |   |   | 0.50 (0.20-1.22) |   |   |   | 0.58 (0.27-1.24) |   |  | 
  
    | Table 4 (C): Logistic regression analyses of alcohol and other drug use (AOD) latent classes on sex behavior outcomes. |