| P no. |
Xolair Dose |
Skin test sensitivity |
SSTa |
Allergic Reaction |
Number
of
Injection |
Efficacy of
Omalizumab |
| 1 |
375 mg q. 2 wk |
Grass, tree, mold, mite |
- |
Aller rhin conj, AD |
78 |
dose 3: AD and NSS improved significantly |
| 2 |
225 mg q. 2 wk |
Grass, mite, cockroach |
+ |
Aller rhin conj, NP, MD Aller, angioedema and UC |
72 |
dose 5: improvement in UC and angioedema attacks and NSS decreased |
| 3 |
225 mg q. 2 wk |
Grass, wheat, tree, mold, mite, cockroach, dog and cat epithelium |
- |
Aller rhin conj, NP |
63 |
dose 3: improvement in NSS |
| 4 |
300 mg q. 2 wk |
Grass, wheat, tree, mold, mite, cockroach, honeybee, dog and cat epithelium |
- |
Aller rhin conj, NP venom aller, bee-sting anaphylaxis and UC |
68 |
dose 1: decrease in NSS, dose 3: improvement in UC, dose 12: no anaphylactic reaction after 48 honey bee-sting. |
| 5 |
300 mg q. 2 wk |
mold, mite, cockroach, tomato, eggplant, strawberry, dog epithelium |
- |
Aller rhin conj, NP, food aller and anaphylaxis (food. induced) |
64 |
dose 1: improvement in NSS
dose 6: tolerated food allergy and no food induced UC |
| 6 |
300 mg q. 2 wk |
Grass, tree, mite, shrimp, perch, egg and latex |
+ |
Aller rhin conj, NP, MD aller, food aller, latex aller, anaphylaxis (NSAID induced) and AD |
72 |
dose 1: NSS decreased
dose 5: AD and food allergy improved significantly
dose 10: improvement in UC and angioedema attacks |
| 7 |
300 mg q. 2 wk |
wheat, tree, mite |
- |
Aller rhin conj, NP, MD Aller and AD dermatitis |
74 |
dose 3: improvement in NSS
dose 5: improvement in UC |
| 8 |
300 mg q. 2 wk |
Grass, tree, mite, kiwi and orange |
- |
Aller rhin conj, NP, MD aller, food aller |
76 |
dose 3: Improvement in UC attacks, NSS and F aller. |
| 9 |
225 mg q. 2 wk |
Grass, wheat, tree, mold, mite, cockroach, honeybee, dog and cat epithelium |
- |
Aller rhin conj, NP, MD Aller, venom aller and AD |
72 |
dose 2: NSS improved
dose 4: no exacerbation in AD |
| 10 |
300mg q. 2 wk |
Grass, mold,
mite,
cockroach |
- |
Aller rhin conj, MD aller, UC |
64 |
dose 4: improvement in UC attacks, NSS |
| 11 |
300mg q. 2 wk |
Grass, tree,
mite, dog epitelia |
- |
Aller rhin conj and AD
|
68 |
dose 2: NSS improves
dose 6: no exacerbation in AD |
AD: Atopic Dermatitis; Aller: Allergy; Conj: Conjunctivitis; MD: mMultidrug; NP: Nasal Polyp; NSAID: Non-Steroidal Anti-Inflammatory Drug; NSS: Nasal Symptom Scoring;
P: Patient; Rhin: Rhinitis; SSTa: Autologous Serum Skin Test; UC: Urticarial
|
