| Grade 0 |
Strong local reaction, diameter larger than 10 cm, longer than 24 h |
| Grade I |
Generalized urticaria, pruritus, nausea |
| Grade II |
Vomiting, angioedema, dizziness, sensation of tightness |
| Grade III |
Dyspnea, stridor, wheezing, fear of dying, weakness, drowsiness |
| Grade IV |
Drop in blood pressure, cyanosis, respiratory arrest, circulatory arrest |
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