Publication |
Target |
Omega 3 supplementation
Intake (from/until) |
Study |
Findings&Summary |
| Dunstan et al. [54] |
pregnant women
with family history of allergic disease |
Fish oil (3.7 g/d n-3 PUFA)
20 w gestation/ until birth |
RDBPC |
Infants were less likely to have a positive skin prick test to egg vs placebo (OR 0,34) at 1 y |
| Lauritzen et al. [55] |
Pregnant women with a fish intake below the population median |
Fish oil (1.5 g/d of n-3 PUFA)
4 mon of lactation |
RDBPC |
No difference in atopic disease and plasma IgE between active and placebo groups |
Furuhjelm et al.
(2009) [56]
(2011) [57] |
pregnant women
with either personal or family history of allergic disease |
1.6 g eicosapentaenoic ac. + 1.1 g docosahexaenoic ac./daily.
25 w gestation/
3-4 m postnatally |
RDBPC |
No effect on the prevalence of clinical symptoms of allergic disease, but a decrease in cumulative incidence of IgE-associated disease during the 1st y.
Decrease in cumulative incidence of IgE-associated disease still remained until 2 y of age |
| Palmer et al. [58] |
pregnant women
with family history of allergic disease |
fish oil (900 mg/d n-3 PUFA)
21 w gestation/ until birth |
RDBPC |
No differences in the overall percentage of infants with Ig E associated food allergy versus placebo. |
