Sea urchin C. elegans Human
N° nodes 127 100 151
N° edges 175 132 202
Clustering coefficient 0.023 0.032 0.028
Diameter 23 23 20
Avg. n° neighbours 2.740 2.620 2.662
Char. path length 8.128 7.816 6.546
The number of nodes represent the total number of molecules involved; the number of edges represents the total number of interactions; the clustering coefficient is calculated as CI=2nI/k(k–1), where nI is the number of links connecting the kI neighbours of node I to each other; the network diameter is the largest distance between two nodes; the Averaged n° neighbours represents the mean number of connections of each node; the Char. path length gives the expected distance between two connected nodes.
Table 1: Main topological parameters of Sea urchin, C. elegans and Human spermatozoa activation networks.
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