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Figure 2: MRM LC-MS/MS chromatograms of a) SHS15 in rat blank plasma b) rat plasma sample spiked with 1.08 μg/mL of SHS15 (LLOQ) c) plasma sample obtained 1.00 hr after intravenous administration of SHS15 to SD rats d) plasma sample obtained 1.00 hr after oral administration of SHS15 to SD rats. |