Mice |
The resting membrane potential of diaphragm muscle, mV |
Junctional region |
Extrajunctional region |
Delta |
Control C57BL/6, 6 months old (8) |
–81.4 ± 0.5
n = 173 |
–78.0 ± 0.4
n = 193 |
3.4 ± 0.6* |
Mdx mice, 6 months old (6) |
–75.1 ± 0.6
n = 106 |
–74.4 ± 0.5
n = 118 |
0.07 |
Mdx mice, 6 months old, 4 months after BMSCs transplantation (6) |
–80.7 ± 0.7
n = 109 |
–77.0 ± 0.6
n = 97 |
3.7 ± 0.9* |
* p < 0.01: Difference between extrajunctional and junctional regions of sarcolemma
n: number of muscle fibers. |