Ensembl Gene ID Description ChromLoc Gene Symbol control(+)/control(-) 48 h control(+)/control(-) 15d
desaturases
ENSG00000099194 stearoyl-CoA desaturase (delta-9-desaturase) chr10q24.31 SCD1 1.2 1.5
ENSG00000145284 stearoyl-CoA desaturase 5 chr4q21.3 SCD5 5.6 1.9
ENSG00000149485 fatty acid desaturase 1 chr11q12.2-q13.1 FADS1 1.7 1.6
DNL (de novo lipogenesis)
ENSG00000132142 acetyl-CoA carboxylase alpha chr17q21 ACACA -1.3 1.5
ENSG00000076555 acetyl-CoA carboxylase beta chr12q24.11 ACACB 4.3 5.0
ENSG00000072310 sterol regulatory element binding transcription factor 1 chr17p11.2 SREBF1 1.3 1.3
ENSG00000198911 sterol regulatory element binding transcription factor 2 chr22q13 SREBF2 -1.3 1.2
elongases
ENSG00000119915 ELOVL fatty acid elongase 3 chr10q24.32 ELOVL3 3.6 1.7
ENSG00000012660 ELOVLfamilymember5,elongationoflongchainfattyacids (FEN1/Elo2, SUR4/Elo3-like, yeast) chr6p21.1-p12.1 ELOVL5 2.2 1.5
phospholipase
ENSG00000184381 phospholipase A2, group VI (cytosolic, calcium-independent) chr22q13.1 PLA2G6 1.40 1.30
Table 3: Changes in the gene expression of enzymes involved in metabolism of fatty acids during SVF cell differentiation. SVF cells were incubated for 48 hours in adipogenic MDI medium for initiation of differentiation (Ctrl (+) 48 h) and then without differentiation factors for 15 days (Ctrl (+) 15d). The negative control cells (Ctrl (-)) were incubated without differentiation factors (microarray (Agilent), n=3, ANOVA p<0.05).
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