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Figure 3: Validation by Q-PCR of differentially expressed genes involved in spermatogenesis in the testes of 35 vs. 5 dpp mice. The genes involved in SSC self-renewal or proliferation showed significant down-regulation (-) in the testes of 35 vs. 5 dpp mice. On the contrary, the genes involved in SSC differentiation and the ones which are expressed in differentiated germ cells showed significant up-regulation (+) in the testes of 35 vs. 5 dpp mice. |