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| Figure 3: CXCL1 induction by CXCL9 is G-protein dependent. Co- Incubation of CXCL9 stimulated GRX cells with pertussis toxin (10 ng/ml) completely abrogates CXCL1 induction (A). This effect is also true for primary hepatic stellate cells, stimulated with either CXCL9 or CXCL10 (B). For (A) three independent experiments were performed, (B) represents three independent cell preparations, measurements were taken in duplicates. Error bars represent SEM values. |
