|
| Figure 2: Genomic organization, mRNA splicing variants and protein sequences of human LYPD6B. The LYPD6B gene consists of 9 exons. Exon 7 to 9 contains the Ly-6 antigen/uPA receptor-like domain (PLAUR domain) and this domain is conserved in all splicing variants. LYPD6B_b variant utilizes different start and stop codons at exon 6 and exon 9 respectively. The LYPD6B_c variant form differs by the splicing out of exon 5. The asterisk shows the mRNA and genomic context localization of the HHSRDSEHTE peptide sequence used for the generation of LYPD6B antibody. (B) Amino acid sequences of LYPD6B isoforms. The boxed amino acid sequences represent the antigen peptide sequence used for LYPD6B antibody. |
