Transcript /Gene

*Expression
Ave. Tumor

*Expression
Ave. Normal

Fold

p-value
Tu vs. Nor

Reference

A.

MUC16 (CA125)

7539

6

1303

8.8×10-16

[9,10]

 

CLAUDIN 4

1570

9

170

1.8×10-19

[15,16]

 

PAX8

1695

15

110

2.6×10-14

[11-13]

 

FOLR1

5281

44

120

1.8×10-9

[14]

B.

LYPD6B

1135

36

31

1.1×10-9

[5]

*Expression based on signal count geometrically averaged from 20 stage IIIC/IV serous ovary cancers and from 8 normal ovaries.  All normal ovaries were also scored as absent expression using Affymetrix absent /present call.

Table 1: General characteristics of known and newly identified ovary cancer transcript up-regulated in stage IIIC/IV serous ovarian cancers.

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