Entonox

Pethidine

P-value

Duration
first stage (hour)
second stage (min)

3.12 ± 1.37
3.44 ± 1.73

2.24 ± 1.07
1.18 ± 1.00

0.001
<0.001

VAS mean score
Befor Analgesia
Over first stage
Over second stage

0.98 ± 9.14
1.53 ± 6.02
1.82 ± 5.70

0.75 ± 9.40
1.25 ± 7.16
1.05 ± 8.22

NS
0.000
0.000

Systolic blood pressure
before analgesia
End of stage 1
End of stage 2

8.95 ± 1.13
8.70 ± 1.12
7.87 ± 1.11

8.37 ± 1.14
56.8 ± 1.11
7.61 ± 1.11

NS
NS
NS

Diastolic blood pressure
before analgesia
End of stage 1
End of stage 2

9.4 ± 6.7
7.87 ± 69.6
7.8 ± 70.20

8.2 ± 66.2
8.65 ± 66.6
8.61 ± 68.2

NS
NS
NS

Heart rate
before analgesia
End of stage 1
End of stage 2

6.84 ± 81.72
11.81 ± 107.1
9.87 ± 109.90

12.22 ± 84.22
10.14 ± 81.9
9.24 ± 80.40

NS
<0.001
<0.001

Respiratory rate
before Analgesia
End of stage 1
End of stage 2

1.50 ± 13.92
1.65 ± 14.16
1.32 ± 13.72

1.51 ± 14.80
1.37 ± 13.52
1.22 ± 12.92

NS
0.03
0.002