Parameter

Difference in combined kidney volume (cm3) (95% CI)

Normal  fetuses       IUGR fetuses      

Fetal biometric indices

 

 

Head circumference (SDS)

0.63 (0.7, 0.98)

0.91 (0.57, 1.23)*

Abdominal circumference (SDS)

1.06 (0.91, 1.56)

1.76 (1.47, 2.05)*

Femur length (SDS)

1.15 (1, 1.67)

1.03 (0.71, 1.35)*

head circumference/ abdominal circumference (SDS

0.78(0.34, 1.67)

1.71 (1.34, 2.09)*

Estimated fetal weight (SDS)

0.71 (0.12, 1.68)

1.77 (1.46, 2.08)*

Doppler indices

 

 

Umbilical artery, PI

-3.17 (-5.5, -0.39)

-2.74 (-4.55, -0.92)

Middle cerebral artery (PI)

-0.64 (-0.18, 1.09)

0.46 (-0.41, 1.33)

Renal artery (PI)

0.91 (0.29, 1.11)

0.87 (0.22, 1.51)*

Renal artery V max

-3.04 (-2.87,-1.16)

-2.14 (-355,-0.68)

PI, pulsatility index; V max, peak systolic velocities with time. SDS, standard deviation score. Values are regression coefficients (95% CI) and reflect the difference in kidney volume per unit increase in fetal growth and fetal blood flow characteristic
Table 4: Associations of fetal biometric indices and Doppler indices with combined fetal kidney volume in both groups after 26 weeks of gestation.
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