| Cause of death (ICD-10th code) |
Number of deathsIMR1 |
Odds ratio |
[95% CI] |
| Singletons |
Twins |
Singletons |
Twins |
|
| Q00-Q07 CMs of the nervous system |
714 (4.1%) |
151 (15.1%) |
0.45 |
4.82 |
10.63 [8.92-12.67]* |
| Q00.0 Anencephaly |
109 |
112 |
0.07 |
3.58 |
51.64 [39.67-67.22]* |
| Q04.2Holoprosencephaly |
200 |
18 |
0.13 |
0.57 |
4.52 [2.79-7.32]* |
| Q10-Q18 CMs of eye, ear, face and neck |
3 |
1 |
0 |
0.03 |
- |
| Q20-Q28 CMs of the circulatory system |
8289 (47.6%) |
451 (45.1%) |
5.27 |
14.41 |
2.74 [2.49-3.01]* |
| Q20.1Double outlet right ventricle |
401 |
12 |
0.26 |
0.38 |
1.5 [0.85-2.67] |
| Q20.3 Discordantventriculoarterial connection |
523 |
23 |
0.73 |
0.33 |
2.21 [1.46-3.34]* |
| Q20.4 Double inlet ventricle |
435 |
11 |
0.28 |
0.35 |
1.27 [0.70- 2.31] |
| Q21.0 Ventricularseptal defect |
662 |
25 |
0.42 |
0.8 |
1.90 [1.27-2.83]* |
| Q21.2 Atrioventricularseptal defect |
636 |
11 |
0.4 |
0.35 |
0.87 [0.48 1.58] |
| Q23.4 Hypoplastic left heart syndrome |
1086 |
29 |
0.69 |
0.93 |
1.34 [0.93-1.94] |
| Q24.9 CM of heart, unspecified |
599 |
23 |
0.38 |
0.73 |
1.93 [1.27-2.93]* |
| Q25.0 Patentductusarteriosus |
542 |
147 |
0.34 |
4.7 |
13.68 [11.36-16.36]* |
| Q25.1 Coarctation of aorta |
469 |
23 |
0.3 |
0.73 |
2.46 [1.62-3.74]* |
| Q25.5 Atresia of pulmonary artery |
309 |
28 |
0.2 |
0.89 |
4.55 [3.09-6.73]* |
| Q26.2 Total anomalous pulmonary venous connection |
576 |
10 |
0.37 |
0.32 |
0.87 [0.47-4.24] |
| Q30-Q34 CMs of the respiratory system |
1947 |
129 |
1.24 |
4.12 |
3.33 [2.79- 3.98]* |
| Q33.6 Hypoplasia and dysplasia of lung |
1567 |
109 |
1 |
3.48 |
3.50 [2.88-4.24]* |
| Q35-Q37 Cleft lip and cleft palate |
15 |
2 |
0.01 |
0.06 |
- |
| Q38-Q45 Other CMs of the digestive system |
526 |
39 |
0.33 |
1.25 |
3.73 [2.69-5.16]* |
| Q50-Q56 CMs of genital organs |
3 |
2 |
0 |
0.06 |
- |
| Q60-Q64 CMs of the urinary system |
574 |
45 |
0.36 |
1.44 |
3.94 [2.91- 5.34]* |
| Q60.6 Potter’s syndrome |
431 |
23 |
0.27 |
0.73 |
2.68 [1.76-4.08]* |
| Q65-Q79 CMs anddeformations of themusculoskeletal system |
1150 |
45 |
0.73 |
1.44 |
1.97 [1.46 -2.65]* |
| Q79.0 Congenital diaphragmatic hernia |
644 |
16 |
0.41 |
0.51 |
1.25 [0.76-2.05] |
| Q80-Q89 Other CMs |
969 |
80 |
0.62 |
2.56 |
4.15 [3.30-5.21]* |
| Q89.4 Conjoined twins |
- |
20 |
- |
0.64 |
- |
| Q90-Q99 Chromosomal abnormalities, not elsewhere classified |
3241 (18.6%) |
56 (5.6%) |
2.06 |
1.79 |
0.87 [0.67-1.13] |
| Q91.3Edwards syndrome, unspecified |
2076 |
29 |
1.32 |
0.93 |
0.70 [0.49 1.01] |
| Q91.7Patau syndrome |
455 |
11 |
0.29 |
0.35 |
1.21 [0.67-2.21] |
| Q00-Q99CMs, deformations and chromosomal abnormalities |
17431 (70.2%) |
1001 (65.7%) |
11.08 |
31.98 |
2.89 [2.71-3.08]* |
Note: 