| |
Progesterone Group(n=30) |
Placebo Group (n=30) |
|
| |
VAS Before treatment |
VAS After treatment |
p |
VAS Before treatment |
VAS After treatment |
p |
p |
| Depression |
4.78 ± 1.28 |
2.34 ± 1.23 |
0.001 |
4.56 ± 1.38 |
2.98 ± 1.60 |
0.003 |
0.06 |
| Irritability |
3.77 ± 0.65 |
1.55 ± 0.88 |
0.001 |
3.78 ± 1.34 |
1.21 ± 0.44 |
0.001 |
0.4 |
| Anxiety |
3.48 ± 1.68 |
1.33 ± 0.12 |
0.001 |
3.11 ± 1.54 |
2.78 ± 1.28 |
0.06 |
0.001 |
| Mood swing |
5.14 ± 1.08 |
3.23 ± 1.28 |
0.001 |
5.71 ± 1.18 |
2.77 ± 1.39 |
0.001 |
0.4 |
| Abdominal bloating |
6.18 ± 2.21 |
2.78 ± 1.18 |
0.001 |
5.63 ± 2.38 |
4.78 ± 2.27 |
0.3 |
0.001 |
| Muscle pain |
3.13 ± 1.45 |
3.41 ± 1.6 |
0.1 |
3.08 ± 1.21 |
2.78 ± 1.28 |
0.5 |
0.3 |
| Food Craving |
3.79 ± 0.78 |
3.22 ± 1.4 |
0.06 |
3.81 ± 1.12 |
2.98 ± 1.73 |
0.6 |
0.1 |
| Felt tired |
2.58 ± 1.62 |
2.21 ± 1.2 |
0.06 |
2.55 ± 1.54 |
1.78 ± 0.28 |
0.001 |
0.001 |
| Sleeplessness |
2.31 ± 1.12 |
1.64 ± 1.23 |
0.001 |
2.48 ± 1.31 |
2.18 ± 1.17 |
0.1 |
0.001 |
| Felt hopeless |
2.55 ± 1.48 |
1.18 ± 0.78 |
0.001 |
2.74 ± 1.23 |
1.58 ± 1.78 |
0.001 |
0.2 |
| Headache |
3.23 ± 1.77 |
3.38 ± 1.44 |
0.1 |
3.78 ± 1.48 |
3.12 ± 1.86 |
0.2 |
0.6 |
| Nausea |
3.18 ± 1.48 |
2.68 ± 1.79 |
0.07 |
3.88 ± 1.32 |
2.11 ± 1.58 |
0.08 |
0.06 |
| Difficulty concentrating |
5.71 ± 2.58 |
4.78 ± 1.28 |
0.04 |
5.44 ± 2.35 |
4.78 ± 1.24 |
0.04 |
0.06 |
| Breast tenderness |
5.78 ± 2.28 |
2.28 ± 1.44 |
0.001 |
5.78 ± 2.18 |
4.78 ± 1.58 |
0.07 |
0.001 |
| Sexual problems |
1.66 ± 1.08 |
1.38 ± 1.18 |
0.5 |
1.33 ± 0.78 |
1.28 ± 1.08 |
0.05 |
0.06 |
| Less interest in usual activities |
4.69 ± 2.19 |
3.78 ± 1.28 |
0.001 |
4.88 ± 2.22 |
3.28 ± 1.28 |
0.001 |
0.05 |
VAS: Visual Anolog Skala
Kruskal-Wallis Test p < 0.05 statistical significant |
