Study |
N |
Timepoint |
OC
(ng/mL) |
BAP
(U/L) |
CTX
(ng/mL) |
[8] |
24 |
Baseline |
5.4 ± 0.8† |
NA |
0.699 ± 0.027 |
|
|
Weight Loss |
6.7 ± 0.9*† |
NA |
0.919 ± 0.036* |
[15] |
17 |
Baseline |
6.6 ± 1.0† |
13.3 ± 2.0† |
0.288 ± 0.032 |
|
|
Weight Loss |
8.3 ± 1.0*† |
12.6 ± 2.0† |
0.327 ± 0.039* |
[8] |
36 |
Baseline |
11.4 ± 0.9† |
17.4 ± 0.7† |
0.607 ± 0.044 |
|
|
Weight Loss |
12.5 ± 1.0* |
17.6 ± 0.7† |
0.700 ± 0.057* |
[14] |
46 |
Lean, active controls |
14.4 ± 0.6 |
24.2 ± 1.2 |
NA |
Data are means ± SEM. NA, not assessed. BMI, body mass index; OC, osteocalcin; BAP, bone-specific alkaline phosphatase; CTX, C-terminal peptide of type I collagen*,
significantly different from Baseline mean within each study; †, significantly different from lean, active controls, P<0.05 |