Column 1 2 3 4 5 6 7 8 9 10 11 Study Author(s) Diagnosis # of patients Hypoglycemia symptoms at home Documented hypoglycemia at home Hypoglycemia symptoms on OGTT Documented hypoglycemia on OGTT Hypoglycemia symptoms with sucrose (or meal tolerance) with acarbose Hypoglycemia symptoms with sucrose (or meal tolerance) with placebo Documented hypoglycemia with sucrose (or meal tolerance) with acarbose Documented hypoglycemia with sucrose (or meal tolerance) with placebo Improvement on short-term follow up Gerard et al. IGT 8 8/8 N/A 8/8 8/8 N/A N/A no no N/A DS 7 7/7 N/A 7/7 7/7 N/A N/A no no N/A idiopat 9 9/9 N/A 9/9 9/9 N/A N/A no yes N/A Richard et al. idiopat 16 16/16 N/A 16/16 13/16 1/16 4/16 0/16 6/16 N/A Ozgen et al. idiopat 21 21/21 N/A 18/21 21/21 N/A N/A N/A N/A 21/21 Peter idiopat 6 6/6 N/A 6/6 6/6 N/A N/A N/A N/A 6/6 Teno et al. DS 1 1/1 1/1 N/A N/A 0/1 0/1 0/1 0/1 N/A Tamura et al. IGT 1 1/1 1/1 N/A 1/1 0/1 0/1 0/1 0/1 1/1 Imhof et al. DS 1 1/1 1/1 1/1 1/1 0/1 1/1 0/1 1/1 1/1 Moreira et al. DS 1 1/1 1/1 N/A N/A N/A N/A N/A N/A 1/1 Yamada el at. DS 1 1/1 N/A 1/1 1/1 N/A N/A N/A N/A 1/1 IGT (Impaired Glucose Tolerance), DS (Dumping syndrome), Idiopat (Idiopathic); OGTT (Oral Glucose Tolerance Test); N/A (Not Applicable). Hypoglycemia is arbitrarily defined as blood glucose < 54 mg/dL Studies evaluating the use of acarbose for treatment of reactive hypoglycemia

Table 1: Studies evaluating the use of acarbose for treatment of reactive Hypoglycemia

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