Values are mean + SEM. (n=5 per group). bP<0.05 significantly different from the control, abP<0.05 significantly different from the diabetic group treated with glibenclamide and amlodipine, acP<0.05 significantly different from the potassium adapted group and adP<0.05 significantly different from the diabetic group. C: Normal saline group K: Potassium adapted group G: Glibenclamide treated group A: Amlodipine treated group AG: group treated with amlodipine and glibenclamide D: Diabetic group DG: Diabetic group treated with glibenclamide DGA: Diabetic group treated with glibenclamide and amlodipine KDG: Potassium adapted diabetic group treated with glibenclamide KDGA: Potassium adapted diabetic group treated with glibenclamide and amlodipine

Figure 2: Effect of K+ adaptation on creatinine clearance of streptozotocin induced diabetic rats treated with amlodipine and glibenclamide.

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