| |
Usual dose® mg/day (maximal dose) |
Tmax®
(h) |
T1/2®
(h) |
Vd®
(l/Kg) |
F®
(%) |
BPP®
(%) |
| Haloperidol |
2-30 (100) |
3-6 |
15-30 |
15-20 |
40-80 |
90-94 |
| Clozapine |
150-450 (900) |
1-6 |
12-36 |
4-8 |
40-60 |
97 |
| Risperidone |
4-16 (16) |
2 |
2,8 |
1-1,5 |
66-82 |
89 |
| Olanzapine |
10-30 (20) |
5-8 |
33 |
10-20 |
60-80 |
93 |
| Quetiapine |
150-750 (800) |
1-1,5 |
5,8-6,6 |
10 |
100 |
83 |
| Ziprasidone |
80-160 |
3,8-5,2 |
3,2-10 |
1,5 |
60 |
> 99 |
| Amisulpride |
400-1200 (1200) |
1,5-4 |
12 |
5,8 |
48 |
16 |
| Aripiprazole |
10-30 (30) |
3-5 |
75-94 |
4,9 |
87 |
99 |
| Paliperidone |
3-12 (15) |
1,5 |
24,8 |
6,9 |
28 |
74 |
F (Bioavailability); BPP (Binding plasmatic proteins). |
