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| Figure 2: Two hypothetical physiologic PPI networks display distinct robustness upon deletion of a hub. Two examples (i-ii) of node-edge diagrams for a hypothetical physiologic PPI network. (Top panels) Networks (i) and (ii) are identical except for 3 differences among the 15 interactions (edges) possessed by each. (Bottom panels) The consequence to each network upon genetic deletion of the gene encoding the protein for hub, K. |
