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| Figure 3: Robustness and signal specificity revealed when quantitative PPI information contributes to PPI network analysis. (Top panel) Binary PPI data provides the network of all known possible interactions for this hypothetical PPI network, previously shown in Figure 2i (gray). Empirical, quantitative physiologic PPI information is overlaid (blue). (Bottom panel) One possible consequence to the network upon prevention or removal of the specific PPI, E:F. |
