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| Figure 2: Expression of each protein of notch signaling pathway in five different scenarios. mRNA expression profile of Gliblastoma Cell Line (GBE) [30], Glioblastoma (GBS), Normal Notch Pathway (NNS), Gamma Secreatase Inhibition (GSI), and two proposed drug treated scenarios; TS2: NICD1 and MAML combinatorial inhibition, and TS1: NICD1 and HIF1A combinatorial inhibition. (A) The expression of the input proteins (B) The expression and simulation results of the intermediate and output proteins |
